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Active Ingredient: Isotretinoin



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Chemical name: Accutane

A systematic though less dynamic improvement was seen until the 32 nd week of the therapy mean number of skin lesions before the therapy - 11.


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Studies on the operon it is with doctors, 25 males; a half of the group received the above treatment regimen while the other half was given isotretinoin locally only. Your reports show improvement from your implants and of unaccented syllables following my head every time?

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In, Mandekou-Lefaki et al.

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The study group consisted of 64 patients 35 females, 29 males divided into 2 groups.

Thirty two subjects from group I received isotretinoin at the dose of 0. In, Amichai et al. The patients were divided into 2 groups according to age: group I — patients aged between 12 and 20 years, and group II — patients aged from 21 to 35 years.

Twenty two patients out of 638 stopped the treatment.

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Improvement in skin lesions was observed, in group I in 94. Within a 4-year observation period, recurrence was found in 3. A similar therapeutic regimen was used by Sardana et al. Prospective studies were carried out on 320 patients diagnosed with moderately severe acne.

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The study was followed by a 6-month observation period. The study was completed by 305 patients. The average cumulative dose taken by patients was 38. Within a 6-month observation period, recurrences occurred in 50 16.

Further information

In, Lee et al. Sixty patients with moderate acne were qualified for the study.


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The subjects were divided into 3 groups; patients in group A were given isotretinoin at the dose of 0. Efficacy, tolerability of the therapy and patient satisfaction were compared in all groups.

What do prescribers need to know?

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