Active Ingredient: Norfloxacin
+ free Noroxin pill.
For how long should it be taken? Take the medicine as long as recommended by the Doctor.
Always ask the doctor before stopping the intake of the drug. What if you take too much overdose? Summarized below are the recommendations made in the guideline update.
The Panel followed a process used in the development of other IDSA guidelines which included a systematic weighting of the quality of the evidence and the grade of recommendation Table 1.
A detailed description of the methods, background, and evidence summaries that support Downloaded from cid.
In some countries and regions, trimethoprim 100 mg twice daily for 3 days is the preferred agent and is considered equivalent to trimethoprim-sulfamethoxazole on the basis of data presented in the original guideline A-III.
Data are insufficient to make a recommendation for other cystitis antimicrobials as to what resistance prevalence should be used to preclude their use for empirical treatment of acute cystitis. The fluoroquinolones, ofloxacin, ciprofloxacin, and levofloxacin, are highly efficacious in 3-day regimens A-I but have a propensity for collateral damage and should be reserved for important uses other than acute cystitis and thus should be considered alternative antimicrobials for acute cystitis A-III.
The b-lactams generally have inferior efficacy and more adverse effects, compared with other UTI antimicrobials B-I. For these reasons, b-lactams other than pivmecillinam should be used with caution for uncomplicated cystitis.
Amoxicillin or ampicillin should not be used for empirical treatment given the relatively poor efficacy, as discussed in the 1999 guidelines and the very high prevalence of antimicrobial resistance to these agents worldwide A-III.
What Is the Treatment for Acute Pyelonephritis? Recommendations 8. In patients suspected of having pyelonephritis, a urine culture and susceptibility test should always be performed, and initial empirical therapy should be tailored appropriately on the basis of the infecting uropathogen A-III.
Contraindications As noted above, under licensed use, norfloxacin is also now considered to be contraindicated for the treatment of certain sexually transmitted diseases by some experts due to bacterial resistance.
Patients taking any of these drugs concomitantly with norfloxacin should be carefully monitored. Pregnancy Norfloxacin has been reported to rapidly cross the blood-placenta and blood-milk barrier, and is extensively distributed into the fetal tissues.